Human ZDHHC19 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	ZDHHC19
Locus ID	131540
Kit Components	GA115147G1, ZDHHC19 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA115147G2, ZDHHC19 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA115147G3, ZDHHC19 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001039617, NM_144637, NR_135617, NR_135618
Synonyms	DHHC19
Summary	Palmitoyltransferase that mediates palmitoylation of STAT3 and RRAS (PubMed:31462771, PubMed:20074548). Palmitoylation of STAT3 induces the homodimerization and transcriptional activation of STAT3, thereby, promoting inflammation and cancer (PubMed:31462771). Palmitoylation of RRAS is linked to cell viability (PubMed:20074548). May be involved in S-stearoylation of STAT3 (Probable).[UniProtKB/Swiss-Prot Function]

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