Human IL31RA activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	IL31RA
Locus ID	133396
Kit Components	GA115197G1, IL31RA gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA115197G2, IL31RA gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA115197G3, IL31RA gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001242636, NM_001242637, NM_001242638, NM_001242639, NM_001297570, NM_001297572, NM_139017
Synonyms	CRL; CRL3; GLM-R; GLMR; GPL; hGLM-R; IL-31RA; PLCA2; PRO21384
Summary	The protein encoded by this gene belongs to the type I cytokine receptor family. This receptor, with homology to gp130, is expressed on monocytes, and is involved in IL-31 signaling via activation of STAT-3 and STAT-5. It functions either as a monomer, or as part of a receptor complex with oncostatin M receptor (OSMR). Several alternatively spliced transcript variants encoding different isoforms have been noted for this gene.[provided by RefSeq, Jun 2011]

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