Human GAB3 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	GAB3
Locus ID	139716
Kit Components	GA115348G1, GAB3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA115348G2, GAB3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA115348G3, GAB3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001081573, NM_001282283, NM_080612, NR_104114
Synonyms	DOS/Gab family member 3; Gab3 protein; Gab3 scaffolding protein; GRB2-associated binding protein 3; OTTHUMP00000026055
Summary	This gene is a member of the GRB2-associated binding protein gene family. These proteins are scaffolding/docking proteins that are involved in several growth factor and cytokine signaling pathways, and they contain a pleckstrin homology domain, and bind SHP2 tyrosine phosphatase and GRB2 adapter protein. The protein encoded by this gene facilitates macrophage differentiation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]

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