Human DOCK11 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	DOCK11
Locus ID	139818
Kit Components	GA115355G1, DOCK11 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA115355G2, DOCK11 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA115355G3, DOCK11 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_144658
Synonyms	ACG; bB128O4.1; ZIZ2
Summary	Guanine nucleotide-exchange factor (GEF) that activates CDC42 by exchanging bound GDP for free GTP. Required for marginal zone (MZ) B-cell development, is associated with early bone marrow B-cell development, MZ B-cell formation, MZ B-cell number and marginal metallophilic macrophages morphology. Facilitates filopodia formation through the activation of CDC42.[UniProtKB/Swiss-Prot Function]

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