Human Prickle (PRICKLE1) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	PRICKLE1
Locus ID	144165
Kit Components	GA115484G1, Prickle gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA115484G2, Prickle gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA115484G3, Prickle gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001144881, NM_001144882, NM_001144883, NM_153026
Synonyms	EPM1B; RILP
Summary	This gene encodes a nuclear receptor that may be a negative regulator of the Wnt/beta-catenin signaling pathway. The encoded protein localizes to the nuclear membrane and has been implicated in the nuclear trafficking of the transcription repressors REST/NRSF and REST4. Mutations in this gene have been linked to progressive myoclonus epilepsy. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 3. [provided by RefSeq, Sep 2009]

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