Human EXOC8 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	EXOC8
Locus ID	149371
Kit Components	GA115705G1, EXOC8 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA115705G2, EXOC8 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA115705G3, EXOC8 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_175876
Synonyms	EXO84; Exo84p; SEC84
Summary	This gene encodes a component of the exocyst complex, an evolutionarily conserved multi-protein complex that plays a critical role in vesicular trafficking and the secretory pathway by targeting post-Golgi vesicles to the plasma membrane. This protein is a target of activated Ral subfamily of GTPases and thereby regulates exocytosis by tethering vesicles to the plasma membrane. Mutations in this gene may be related to Joubert syndrome. [provided by RefSeq, Sep 2016]

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