Human CLDN19 activation kit by CRISPRa

CAT#: GA115709

CLDN19 CRISPRa kit - CRISPR gene activation of human claudin 19



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CNY 12255.00


货期*
4周

规格
    • 1 kit

Product images

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Specifications

Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol CLDN19
Locus ID 149461
Kit Components

GA115709G1, CLDN19 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA115709G2, CLDN19 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA115709G3, CLDN19 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Reference Data
RefSeq NM_001123395, NM_001185117, NM_148960
Synonyms HOMG5
Summary The product of this gene belongs to the claudin family. It plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity. Defects in this gene are the cause of hypomagnesemia renal with ocular involvement (HOMGO). HOMGO is a progressive renal disease characterized by primary renal magnesium wasting with hypomagnesemia, hypercalciuria and nephrocalcinosis associated with severe ocular abnormalities such as bilateral chorioretinal scars, macular colobomata, significant myopia and nystagmus. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jun 2010]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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