Human SH3D19 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	SH3D19
Locus ID	152503
Kit Components	GA115835G1, SH3D19 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA115835G2, SH3D19 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA115835G3, SH3D19 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001009555, NM_001128923, NM_001128924, NM_001243349
Synonyms	EBP; EVE1; Kryn; SH3P19
Summary	This gene encodes a multiple SH3 domain-containing protein, which interacts with other proteins, such as EBP and members of ADAM family, via the SH3 domains. This protein may be involved in suppression of Ras-induced cellular transformation and Ras-mediated activation of ELK1 by EBP, and regulation of ADAM proteins in the signaling of EGFR-ligand shedding. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011]

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