Human ATP6V0E2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	ATP6V0E2
Locus ID	155066
Kit Components	GA115910G1, ATP6V0E2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA115910G2, ATP6V0E2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA115910G3, ATP6V0E2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001100592, NM_001289990, NM_145230, NR_110612, NM_001367788, NM_001367789, NM_001367791, NM_001367792, NM_001367793, NM_001367794, NM_001367796, NM_001367797, NM_001367795
Synonyms	ATP6V0E2L; C7orf32
Summary	Multisubunit vacuolar-type proton pumps, or H(+)-ATPases, acidify various intracellular compartments, such as vacuoles, clathrin-coated and synaptic vesicles, endosomes, lysosomes, and chromaffin granules. H(+)-ATPases are also found in plasma membranes of specialized cells, where they play roles in urinary acidification, bone resorption, and sperm maturation. Multiple subunits form H(+)-ATPases, with proteins of the V1 class hydrolyzing ATP for energy to transport H+, and proteins of the V0 class forming an integral membrane domain through which H+ is transported. ATP6V0E2 encodes an isoform of the H(+)-ATPase V0 e subunit, an essential proton pump component (Blake-Palmer et al., 2007 [PubMed 17350184]).[supplied by OMIM, Mar 2008]

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