Human OTUD7A activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	OTUD7A
Locus ID	161725
Kit Components	GA116030G1, OTUD7A gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA116030G2, OTUD7A gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA116030G3, OTUD7A gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001329907, NM_130901
Synonyms	C15orf16; C16ORF15; CEZANNE2; OTUD7
Summary	The protein encoded by this gene is a deubiquitinizing enzyme and possible tumor suppressor. The encoded protein acts on TNF receptor associated factor 6 (TRAF6) to control nuclear factor kappa B expression. However, this gene is downregulated by SNAIL1 in hepatocellular carcinoma cells, contributing to their progression and malignancy. [provided by RefSeq, Aug 2016]

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