Human EID2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	EID2
Locus ID	163126
Kit Components	GA116078G1, EID2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA116078G2, EID2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA116078G3, EID2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_153232
Synonyms	CRI2; EID-2
Summary	Interacts with EP300 and acts as a repressor of MYOD-dependent transcription and muscle differentiation. Inhibits EP300 histone acetyltransferase activity. Acts as a repressor of TGFB/SMAD transcriptional responses. May act as a repressor of the TGFB/SMAD3-dependent signaling by selectively blocking formation of TGFB-induced SMAD3-SMAD4 complex.[UniProtKB/Swiss-Prot Function]

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