Human Laeverin (LVRN) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	LVRN
Locus ID	206338
Kit Components	GA116467G1, Laeverin gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA116467G2, Laeverin gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA116467G3, Laeverin gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_173800
Synonyms	APQ; AQPEP; TAQPEP
Summary	Metalloprotease which may be important for placentation by regulating biological activity of key peptides at the embryo-maternal interface. On synthetic substrates it shows a marked preference for Leu-4-methylcoumaryl-7-amide (Leu-MCA) over Met-MCA, Arg-LCA and Lys-LCA. Cleaves the N-terminal amino acid of several peptides such as angiotensin-3, kisspeptin-10 and endokinin C.[UniProtKB/Swiss-Prot Function]

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