Human FAM123A (AMER2) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	AMER2
Locus ID	219287
Kit Components	GA116472G1, FAM123A gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA116472G2, FAM123A gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA116472G3, FAM123A gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_152704, NM_199138
Synonyms	FAM123A
Summary	Negative regulator of the canonical Wnt signaling pathway involved in neuroectodermal patterning. Acts by specifically binding phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2), translocating to the cell membrane and interacting with key regulators of the canonical Wnt signaling pathway, such as components of the beta-catenin destruction complex.[UniProtKB/Swiss-Prot Function]

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