Human Two pore calcium channel protein 2 (TPCN2) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	TPCN2
Locus ID	219931
Kit Components	GA116532G1, Two pore calcium channel protein 2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA116532G2, Two pore calcium channel protein 2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA116532G3, Two pore calcium channel protein 2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_139075
Synonyms	SHEP10; TPC2
Summary	This gene encodes a putative cation-selective ion channel with two repeats of a six-transmembrane-domain. The protein localizes to lysosomal membranes and enables nicotinic acid adenine dinucleotide phosphate (NAADP) -induced calcium ion release from lysosome-related stores. This ubiquitously expressed gene has elevated expression in liver and kidney. Two common nonsynonymous SNPs in this gene strongly associate with blond versus brown hair pigmentation.[provided by RefSeq, Dec 2009]

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