Human HEPACAM2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	HEPACAM2
Locus ID	253012
Kit Components	GA116736G1, HEPACAM2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA116736G2, HEPACAM2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA116736G3, HEPACAM2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001039372, NM_001288804, NM_001288810, NM_198151, NM_001346642
Synonyms	MIKI
Summary	This gene encodes a protein related to the immunoglobulin superfamily that plays a role in mitosis. Knockdown of this gene results in prometaphase arrest, abnormal nuclear morphology and apoptosis. Poly(ADP-ribosylation) of the encoded protein promotes its translocation to centrosomes, which may stimulate centrosome maturation. A chromosomal deletion including this gene may be associated with myeloid leukemia and myelodysplastic syndrome in human patients. [provided by RefSeq, Oct 2016]

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