Human RUFY4 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	RUFY4
Locus ID	285180
Kit Components	GA117197G1, RUFY4 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA117197G2, RUFY4 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA117197G3, RUFY4 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_198483, NR_034176
Synonyms	ZFYVE31
Summary	Positively regulates macroautophagy in primary dendritic cells. Increases autophagic flux, probably by stimulating both autophagosome formation and facilitating tethering with lysosomes. Binds to phosphatidylinositol 3-phosphate (PtdIns3P) through its FYVE-type zinc finger.[UniProtKB/Swiss-Prot Function]

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