Human AER61 (EOGT) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	EOGT
Locus ID	285203
Kit Components	GA117201G1, AER61 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA117201G2, AER61 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA117201G3, AER61 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001278689, NM_173654, NR_103826
Synonyms	AER61; AOS4; C3orf64; EOGT1
Summary	This gene encodes an enzyme that acts in the lumen of the endoplasmic reticulum to catalyze the transfer of N-acetylglucosamine to serine or threonine residues of extracellular-targeted proteins. This enzyme modifies proteins containing eukaryotic growth factor (EGF)-like domains, including the Notch receptor, thereby regulating developmental signalling. Mutations in this gene have been observed in individuals with Adams-Oliver syndrome 4. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2015]

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