Human ZC3H12D activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	ZC3H12D
Locus ID	340152
Kit Components	GA117461G1, ZC3H12D gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA117461G2, ZC3H12D gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA117461G3, ZC3H12D gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_207360
Synonyms	C6orf95; dJ281H8.1; MCPIP4; p34; TFL
Summary	May regulate cell growth likely by suppressing RB1 phosphorylation (PubMed:19531561). May function as RNase and regulate the levels of target RNA species (Potential). In association with ZC3H12A enhances the degradation of interleukin IL-6 mRNA level in activated macrophages (PubMed:26134560). Serve as a tumor suppressor in certain leukemia cells (PubMed:17210687). Overexpression inhibits the G1 to S phase progression through suppression of RB1 phosphorylation (PubMed:19531561).[UniProtKB/Swiss-Prot Function]

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