Human C1orf187 (DRAXIN) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	DRAXIN
Locus ID	374946
Kit Components	GA117795G1, C1orf187 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA117795G2, C1orf187 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA117795G3, C1orf187 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_198545
Synonyms	AGPA3119; C1orf187; neucrin; UNQ3119
Summary	Chemorepulsive axon guidance protein required for the development of spinal cord and forebrain commissures. Acts as a chemorepulsive guidance protein for commissural axons during development. Able to inhibit or repel neurite outgrowth from dorsal spinal cord. Inhibits the stabilization of cytosolic beta-catenin (CTNNB1) via its interaction with LRP6, thereby acting as an antagonist of Wnt signaling pathway.[UniProtKB/Swiss-Prot Function]

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