Human NPSR1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	NPSR1
Locus ID	387129
Kit Components	GA117878G1, NPSR1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA117878G2, NPSR1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA117878G3, NPSR1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001300933, NM_001300934, NM_001300935, NM_207172, NM_207173
Synonyms	ASRT2; GPR154; GPRA; NPSR; PGR14; VRR1
Summary	This gene encodes a member of the vasopressin/oxytocin subfamily of G protein-coupled receptors. The encoded membrane protein acts as a receptor for neuropeptide S and affects a variety of cellular processes through its signaling. Increased expression of this gene in ciliated cells of the respiratory epithelium and in bronchial smooth muscle cells is associated with asthma. Polymorphisms in this gene have also been associated with asthma susceptibility, panic disorders, inflammatory bowel disease, and rheumatoid arthritis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]

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