Human TARM1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	TARM1
Locus ID	441864
Kit Components	GA118527G1, TARM1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA118527G2, TARM1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA118527G3, TARM1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001135686, NM_001330650
Synonyms	OLT-2
Summary	May act as receptor (By similarity). Negatively regulates TCR-mediated CD4(+) T cell proliferation and activation, possibly by binding an unknown ligand on the T cell surface (PubMed:26311901). Enhances Toll-like receptor-mediated production of pro-inflammatory cytokines by macrophages and neutrophils (By similarity).[UniProtKB/Swiss-Prot Function]

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