Human BECN2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	BECN2
Locus ID	441925
Kit Components	GA118532G1, BECN2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA118532G2, BECN2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA118532G3, BECN2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001290693
Synonyms	BECN1L1; BECN1P1
Summary	Involved in 2 distinct lysosomal degradation pathways: acts as a regulator of autophagy and as a regulator of G-protein coupled receptors turnover. Regulates degradation in lysosomes of a variety of G-protein coupled receptors via its interaction with GPRASP1/GASP1.[UniProtKB/Swiss-Prot Function]

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