Human HEPN1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	HEPN1
Locus ID	641654
Kit Components	GA118658G1, HEPN1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA118658G2, HEPN1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA118658G3, HEPN1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001037558
Synonyms	cancer susceptibility gene HEPN1; HEPACAM opposite strand 1
Summary	This gene is expressed predominantly in the liver. Transient transfection studies show the expression of this gene significantly inhibits cell growth, suggesting a role for this gene in apoptosis. Expression of this gene is down-regulated or lost in hepatocellular carcinomas (HCC), suggesting that loss of this gene is involved in carcinogenesis of hepatocytes (PMID:12971969). This gene maps to the 3'-noncoding region of the HEPACAM gene (GeneID:220296) on the antisense strand. [provided by RefSeq, Aug 2020]

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