Human RAD21L1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	RAD21L1
Locus ID	642636
Kit Components	GA118669G1, RAD21L1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA118669G2, RAD21L1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA118669G3, RAD21L1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001136566
Synonyms	dJ545L17.2; RAD21L
Summary	Meiosis-specific component of some cohesin complex required during the initial steps of prophase I in male meiosis. Probably required during early meiosis in males for separation of sister chromatids and homologous chromosomes. Replaces RAD21 in premeiotic S phase (during early stages of prophase I), while RAD21 reappears in later stages of prophase I. Involved in synaptonemal complex assembly, synapsis initiation and crossover recombination between homologous chromosomes during prophase I (By similarity).[UniProtKB/Swiss-Prot Function]

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