Mouse Aif1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Aif1
Locus ID	11629
Kit Components	GA200137G1, Aif1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA200137G2, Aif1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA200137G3, Aif1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_019467, NM_001361501, NM_001361502
Synonyms	AI607846; AIF-1; D17H6S50E; G1; Iba1
Summary	Actin-binding protein that enhances membrane ruffling and RAC activation. Enhances the actin-bundling activity of LCP1. Binds calcium. Plays a role in RAC signaling and in phagocytosis. May play a role in macrophage activation and function. Promotes the proliferation of vascular smooth muscle cells and of T-lymphocytes. Enhances lymphocyte migration. Plays a role in vascular inflammation.[UniProtKB/Swiss-Prot Function]

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