Mouse Ap3d1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Ap3d1
Locus ID	11776
Kit Components	GA200215G1, Ap3d1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA200215G2, Ap3d1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA200215G3, Ap3d1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_007460
Synonyms	AA407035; Ap3d; Bolvr; mBLVR1; mh; mocha
Summary	Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes (By similarity). Involved in process of CD8+ T-cell and NK cell degranulation (By similarity). In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals (PubMed:21998198).[UniProtKB/Swiss-Prot Function]

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