Mouse Apaf1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Apaf1
Locus ID	11783
Kit Components	GA200220G1, Apaf1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA200220G2, Apaf1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA200220G3, Apaf1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001042558, NM_001282947, NM_009684
Synonyms	6230400I06Rik; Apaf-1; Apaf1l; fog; mKIAA0413
Summary	Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP (By similarity).[UniProtKB/Swiss-Prot Function]

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