Mouse Atf1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Atf1
Locus ID	11908
Kit Components	GA200304G1, Atf1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA200304G2, Atf1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA200304G3, Atf1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_007497
Summary	Binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Binds to the Tax-responsive element (TRE) of HTLV-I. Mediates PKA-induced stimulation of CRE-reporter genes. Represses the expression of FTH1 and other antioxidant detoxification genes. Triggers cell proliferation and transformation (By similarity).[UniProtKB/Swiss-Prot Function]

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