Mouse Bach2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Bach2
Locus ID	12014
Kit Components	GA200363G1, Bach2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA200363G2, Bach2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA200363G3, Bach2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001109661, NM_007521
Synonyms	E030004N02Rik
Summary	Transcriptional regulator that acts as repressor or activator (PubMed:8887638). Binds to Maf recognition elements (MARE) (PubMed:8887638). Plays an important role in coordinating transcription activation and repression by MAFK (PubMed:8887638). Induces apoptosis in response to oxidative stress through repression of the antiapoptotic factor HMOX1 (By similarity). Positively regulates the nuclear import of actin (PubMed:26021350).[UniProtKB/Swiss-Prot Function]

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