Mouse Bglap activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Bglap
Locus ID	12096
Kit Components	GA200402G1, Bglap gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA200402G2, Bglap gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA200402G3, Bglap gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001037939, NM_007541
Synonyms	Bglap1; mOC-A; OC; OG1
Summary	This gene encodes one of the most abundant non-collagenous proteins in bone tissue that is localized to the mineralized matrix of bone. The encoded preproprotein undergoes proteolytic processing and post-translational gamma carboxylation to generate a mature, calcium-binding protein. Mice lacking the encoded protein develop abnormalities of bone remodelling. This gene is located adjacent to two other osteocalcin-related genes on chromosome 3. [provided by RefSeq, Oct 2015]

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