Mouse Calr activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Calr
Locus ID	12317
Kit Components	GA200501G1, Calr gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA200501G2, Calr gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA200501G3, Calr gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_007591
Synonyms	Calregulin; CRT
Summary	Calcium-binding chaperone that promotes folding, oligomeric assembly and quality control in the endoplasmic reticulum (ER) via the calreticulin/calnexin cycle. This lectin interacts transiently with almost all of the monoglucosylated glycoproteins that are synthesized in the ER. Interacts with the DNA-binding domain of NR3C1 and mediates its nuclear export. Involved in maternal gene expression regulation. May participate in oocyte maturation via the regulation of calcium homeostasis (By similarity).[UniProtKB/Swiss-Prot Function]

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