Mouse Cd24a activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Cd24a
Locus ID	12484
Kit Components	GA200608G1, Cd24a gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA200608G2, Cd24a gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA200608G3, Cd24a gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_009846
Synonyms	Cd24; HSA; Ly-52; nectadrin
Summary	May have a pivotal role in cell differentiation of different cell types. May have a specific role in early thymocyte development. Signaling could be triggered by the binding of a lectin-like ligand to the CD24 carbohydrates, and transduced by the release of second messengers derived from the GPI-anchor. Modulates B-cell activation responses (By similarity). In association with SIGLEC10 may be involved in the selective suppression of the immune response to danger-associated molecular patterns (DAMPs) such as HMGB1, HSP70 and HSP90 (PubMed:19264983). Plays a role in the control of autoimmunity (PubMed:20200274).[UniProtKB/Swiss-Prot Function]

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