Mouse Clk1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Clk1
Locus ID	12747
Kit Components	GA200757G1, Clk1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA200757G2, Clk1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA200757G3, Clk1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001042634, NM_009905, NR_027853, NR_027854
Synonyms	STY
Summary	Dual specificity kinase acting on both serine/threonine and tyrosine-containing substrates. Phosphorylates serine- and arginine-rich (SR) proteins of the spliceosomal complex and may be a constituent of a network of regulatory mechanisms that enable SR proteins to control RNA splicing. Phosphorylates: SRSF1, SRSF3 and PTPN1. Regulates the alternative splicing of tissue factor (F3) pre-mRNA in endothelial cells and adenovirus E1A pre-mRNA.[UniProtKB/Swiss-Prot Function]

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