Mouse Clk4 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Clk4
Locus ID	12750
Kit Components	GA200759G1, Clk4 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA200759G2, Clk4 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA200759G3, Clk4 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001304744, NM_007714, NM_001362535, NM_001362536, NM_001362538, NM_001362539, NM_001362540, NM_001362541
Synonyms	AI987988; C85119
Summary	Dual specificity kinase acting on both serine/threonine and tyrosine-containing substrates. Phosphorylates serine- and arginine-rich (SR) proteins of the spliceosomal complex and may be a constituent of a network of regulatory mechanisms that enable SR proteins to control RNA splicing. Phosphorylates SRSF1 and SRSF3. Required for the regulation of alternative splicing of MAPT/TAU. Regulates the alternative splicing of tissue factor (F3) pre-mRNA in endothelial cells.[UniProtKB/Swiss-Prot Function]

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