Mouse Ccr4 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Ccr4
Locus ID	12773
Kit Components	GA200775G1, Ccr4 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA200775G2, Ccr4 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA200775G3, Ccr4 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_009916
Synonyms	C-C CKR-4; CHEMR1; Cmkbr4; LESTR; Sdf1r
Summary	High affinity receptor for the C-C type chemokines CCL17/TARC and CCL22/MDC. The activity of this receptor is mediated by G(i) proteins which activate a phosphatidylinositol-calcium second messenger system. Could play a role in lipopolysaccharide (LPS)-induced endotoxic shock. In the CNS, could mediate hippocampal-neuron survival.[UniProtKB/Swiss-Prot Function]

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