Mouse Col1a2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Col1a2
Locus ID	12843
Kit Components	GA200830G1, Col1a2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA200830G2, Col1a2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA200830G3, Col1a2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_007743
Synonyms	AA960264; AI325291; Col1a-2; Cola-2; Cola2; oim
Summary	This gene encodes the alpha-2 subunit of the fibril-forming type I collagen, the most abundant protein of bone, skin and tendon extracellular matrices. The encoded protein, in association with alpha-1 subunit, forms heterotrimeric type I procollagen that undergoes proteolytic processing during fibril formation. Mice harboring certain mutations in the encoded gene exhibit symptoms of moderate to severe forms of osteogenesis imperfecta. [provided by RefSeq, Dec 2015]

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