Mouse Comt activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Comt
Locus ID	12846
Kit Components	GA200832G1, Comt gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA200832G2, Comt gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA200832G3, Comt gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001111062, NM_001111063, NM_007744
Synonyms	Comt1; D16Wsu103e; D330014B15Rik
Summary	Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones. Also shortens the biological half-lives of certain neuroactive drugs, like L-DOPA, alpha-methyl DOPA and isoproterenol.[UniProtKB/Swiss-Prot Function]

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