Mouse Cpt2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Cpt2
Locus ID	12896
Kit Components	GA200861G1, Cpt2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA200861G2, Cpt2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA200861G3, Cpt2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_009949
Synonyms	AI323697; CPTII
Summary	Involved in the intramitochondrial synthesis of acylcarnitines from accumulated acyl-CoA metabolites. Reconverts acylcarnitines back into the respective acyl-CoA esters that can then undergo beta-oxidation, an essential step for the mitochondrial uptake of long-chain fatty acids and their subsequent beta-oxidation in the mitochondrion. Active with medium (C8-C12) and long-chain (C14-C18) acyl-CoA esters.[UniProtKB/Swiss-Prot Function]

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