Mouse Cradd activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Cradd
Locus ID	12905
Kit Components	GA200864G1, Cradd gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA200864G2, Cradd gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA200864G3, Cradd gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001330138, NM_001330141, NM_001330175, NM_009950
Synonyms	RAIDD
Summary	Adapter protein that associates with PIDD1 and the caspase CASP2 to form the PIDDosome, a complex that activates CASP2 and triggers apoptosis. Also recruits CASP2 to the TNFR-1 signaling complex through its interaction with RIPK1 and TRADD and may play a role in the tumor necrosis factor-mediated signaling pathway.[UniProtKB/Swiss-Prot Function]

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