Mouse Crx activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Crx
Locus ID	12951
Kit Components	GA200891G1, Crx gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA200891G2, Crx gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA200891G3, Crx gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001113330, NM_007770
Synonyms	Crx1
Summary	Transcription factor that binds and transactivates the sequence 5'-TAATC[CA]-3' which is found upstream of several photoreceptor-specific genes, including the opsin genes. Acts synergistically with other transcription factors, such as NRL, RORB and RAX, to regulate photoreceptor cell-specific gene transcription. Essential for the maintenance of mammalian photoreceptors.[UniProtKB/Swiss-Prot Function]

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