Mouse Cyp24a1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Cyp24a1
Locus ID	13081
Kit Components	GA200974G1, Cyp24a1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA200974G2, Cyp24a1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA200974G3, Cyp24a1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_009996
Synonyms	24-OHase; CP24; Cyp24
Summary	The protein encoded by this gene localizes to the mitochondrion, where it degrades calcitriol to calcitetrol. This gene is upregulated by binding of calcitriol to the upstream regulatory region and to a downstream enhancer region, thereby allowing calcitriol to autoregulate its concentration in the cell. The encoded protein may also play a role in calcium homeostasis. [provided by RefSeq, Aug 2015]

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