Mouse Slc25a1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Slc25a1
Locus ID	13358
Kit Components	GA201067G1, Slc25a1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA201067G2, Slc25a1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA201067G3, Slc25a1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_153150
Synonyms	1300019P08Rik; 2610100G11Rik; AI194714; Ctp; Dgsj; Slc20a3
Summary	Citrate transporter that mediates the exchange of mitochondrial citrate for cytosolic malate. Also able to mediate the exchange of citrate for isocitrate, phosphoenolpyruvate, cis- but not trans-aconitate and to a lesser extend maleate and succinate. Important for the bioenergetics of hepatic cells as it provides a carbon source for fatty acid and sterol biosyntheses, and NAD(+) for the glycolytic pathway. Required for proper neuromuscular junction formation.[UniProtKB/Swiss-Prot Function]

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