Mouse Dmp1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Dmp1
Locus ID	13406
Kit Components	GA201094G1, Dmp1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA201094G2, Dmp1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA201094G3, Dmp1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_016779, NM_001359013
Synonyms	AV020965; Dmp; PP
Summary	May have a dual function during osteoblast differentiation. In the nucleus of undifferentiated osteoblasts, unphosphorylated form acts as a transcriptional component for activation of osteoblast-specific genes like osteocalcin. During the osteoblast to osteocyte transition phase it is phosphorylated and exported into the extracellular matrix, where it regulates nucleation of hydroxyapatite (By similarity).[UniProtKB/Swiss-Prot Function]

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