Mouse Dync1i2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Dync1i2
Locus ID	13427
Kit Components	GA201104G1, Dync1i2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA201104G2, Dync1i2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA201104G3, Dync1i2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001198872, NM_001198873, NM_001198874, NM_001198875, NM_001198876, NM_001198877, NM_001198878, NM_001347173, NM_010064
Synonyms	3110079H08Rik; AW554389; Dncic2
Summary	Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. The intermediate chains mediate the binding of dynein to dynactin via its 150 kDa component (p150-glued) DCNT1. Involved in membrane-transport, such as Golgi apparatus, late endosomes and lysosomes (By similarity).[UniProtKB/Swiss-Prot Function]

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