Mouse Adam28 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Adam28
Locus ID	13522
Kit Components	GA201143G1, Adam28 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA201143G2, Adam28 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA201143G3, Adam28 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001048175, NM_010082, NM_176991, NM_183366, NR_102399
Synonyms	C130072N01Rik; D430033C21Rik; Dtgn1; eMDCII; MDC-L; MDCL; TECADAM
Summary	This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are typically membrane-anchored, although a form of this protein may be secreted. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate a mature protein product. This protein may bind to integrins and regulate lymphocyte migration by enhancing cell adhesion. [provided by RefSeq, Aug 2015]

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