Mouse Eps15l1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Eps15l1
Locus ID	13859
Kit Components	GA201276G1, Eps15l1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA201276G2, Eps15l1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA201276G3, Eps15l1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001122832, NM_001289859, NM_007944
Synonyms	9830147J04Rik; AI593686; Eps15-rs; Eps15R
Summary	Seems to be a constitutive component of clathrin-coated pits that is required for receptor-mediated endocytosis. Involved in endocytosis of integrin beta-1 (ITGB1) and transferrin receptor (TFR); internalization of ITGB1 as DAB2-dependent cargo but not TFR seems to require association with DAB2 (By similarity).[UniProtKB/Swiss-Prot Function]

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