Mouse Mecom activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Mecom
Locus ID	14013
Kit Components	GA201313G1, Mecom gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA201313G2, Mecom gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA201313G3, Mecom gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_007963, NM_021442, NM_001361034, NM_001370768, NM_001370769
Synonyms	D630039M04Rik; Evi-1; Evi1; Jbo; Mds; Mds1; Mds1-Evi1; Prdm3; Znfpr1b1
Summary	Isoform 1: Functions as a transcriptional regulator binding to DNA sequences in the promoter region of target genes and regulating positively or negatively their expression. Oncogene which plays a role in development, cell proliferation and differentiation. May also play a role in apoptosis through regulation of the JNK and TGF-beta signaling. Involved in hematopoiesis.[UniProtKB/Swiss-Prot Function]

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