Mouse Acsl1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Acsl1
Locus ID	14081
Kit Components	GA201349G1, Acsl1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA201349G2, Acsl1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA201349G3, Acsl1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001302163, NM_007981
Synonyms	Acas; Acas1; Acs; Facl2; FACS; LACS 1; LACS1
Summary	The protein encoded by this gene belongs to a family of acyl coenzyme A synthetase proteins, which convert long chain fatty acids to acyl CoA products via an ATP-dependent pathway. This enzyme is enriched in heart, liver and adipose tissue, where it functions in lipid synthesis and mitochondrial and peroxisomal beta-oxidation. In addition, it is expressed in monocytes and macrophages where it appears to have a functionally distinct role in mediating inflammatory and innate immune responses. A pseudogene of this gene is found on chromosome 5. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2014]

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