Mouse Fgf2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Fgf2
Locus ID	14173
Kit Components	GA201400G1, Fgf2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA201400G2, Fgf2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA201400G3, Fgf2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_008006
Synonyms	bFGF; Fgf-2; Fgfb
Summary	Acts as a ligand for FGFR1, FGFR2, FGFR3 and FGFR4. Also acts as an integrin ligand which is required for FGF2 signaling. Binds to integrin ITGAV:ITGB3. Plays an important role in the regulation of cell survival, cell division, cell differentiation and cell migration. Functions as a potent mitogen in vitro. Can induce angiogenesis.[UniProtKB/Swiss-Prot Function]

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