Mouse Aktip activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Aktip
Locus ID	14339
Kit Components	GA201484G1, Aktip gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA201484G2, Aktip gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA201484G3, Aktip gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001302266, NM_001302267, NM_001302268, NM_001302337, NM_010241, NM_001358934, NM_001358935, NM_001358936, NM_001358937, NM_001358938
Synonyms	AL023020; Fif; Ft; Ft1; Fts
Summary	Component of the FTS/Hook/FHIP complex (FHF complex). The FHF complex may function to promote vesicle trafficking and/or fusion via the homotypic vesicular protein sorting complex (the HOPS complex). Regulates apoptosis by enhancing phosphorylation and activation of AKT1. Increases release of TNFSF6 via the AKT1/GSK3B/NFATC1 signaling cascade (By similarity).[UniProtKB/Swiss-Prot Function]

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